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Pathogenicity and Health Effects
Aspergillus
granulosus
is a causative
agent of disseminated infection among cardiac transplant recipients.
Macroscopic Appearance
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Growth rate is moderate to rapid and texture of colonies varies from plane
to irregularly furrowed, frequently floccose, with uneven texture, and
have a granular appearance due to formation of small
hülle
cell aggregates which may at first resemble
sclerotia; and
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Surface colony color is buff to ochraceous to dull brown while reverse is
dark yellow to reddish brown; and
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Presence of pale blue – green colored conidial heads may contribute color
pigmentation; however, in some strains their production may be minimal
that this color pigmentation may not manifest.
Microscopic Appearance
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Conidial heads are radiate and
hyphae are septate and hyaline;
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Conidiophores are thin – walled, pale brown, smooth, and are 350 - 500 µm
long as described by Raper and Fennell, on the other hand, the Fungus
Testing Laboratory has measured an isolate with very long conidiophores of
up to over 1 mm;
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Vesicles are biseriate, elliptical, with diameter of 12 – 18 µm, and with
almost the entire surface being covered;
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Conidia are globose, finely roughened, pale green, and with diameter of
3.5 – 5.5 µm; and
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Hülle cells
are sub – globose to ovoid to quite elongate, with size ranging from 12 –
30 µm long, appear numerous in freshly isolated chains, and occur in
colorless clusters.
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